Hepatitis B Infection is most prevalent chronic infection in India. It is associated with Hepatocellular carcinoma in chronic carrier. It is also responsible for chronic hepatitis and hepatic failure in large number of population. It is almost more than a decade Hepatitis B vaccination was included in National Immunization Programme (NIP). Still hepatitis B continues to be a major health Issue. In this review article we have discussed about role of vaccination in Hepatitis B infection in Indian scenario.
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